Plasma Derived Medicinal Products (PDMPs)
PDMPs are Plasma-derived medicinal products, made by industry out of donated plasma.
Plasma derived medicinal products (PDMPs) are prepared industrially from human plasma by pharmaceutical companies and are life-saving therapeutics for large communities of patients.
PDMPs are used in very different circumstances:
- For people with primary immunodeficiencies (immunoglobulin)
- For patients suffering from haemophilia and other bleeding disorders
- For patients with antitrypsin deficiency
For people diagnosed with Guillain-Barré syndrome (GBS), chronic inflammatory demyelinating neuropathy (CIDP) and multifocal motor neuropathy (MMN)
- To stop a crisis in hereditary angioedema
- In end stage liver failure (cirrhosis)
- In shock, trauma and burn emergencies,
among other uses.
List of PDMPs
For primary immunodeficiencies:
- Intravenous immunoglobulin: 5%, 10%,
- Subcutaneous immunoglobulin: 10%, 16%, 16,5%, 20%,
- Plasma- derived Factor Concentrates: factors XIII, II, VII, IX, X
For alpha-1 antitrypsin deficiency:
- Human alpha1-proteinase inhibitor
For chronic inflammatory demyelinating neuropathy and multifocal motor neuropathy:
Intravenous immunoglobuline / Subcutanous immunoglobulin